{"id":56885,"date":"2024-07-03T12:04:27","date_gmt":"2024-07-03T12:04:27","guid":{"rendered":"https:\/\/english.saigonbiz.com.vn\/2024\/07\/03\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/"},"modified":"2024-07-03T12:04:27","modified_gmt":"2024-07-03T12:04:27","slug":"immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results","status":"publish","type":"post","link":"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/","title":{"rendered":"Immutep Announces Details for Oral Presentation at ESMO Virtual Plenary Session and Webcast to Discuss Clinical Results"},"content":{"rendered":"
\n

Company to Host Webcast on 12th July at 9am AEST (7pm ET, 11 July)<\/em><\/p>\n

SYDNEY, AUSTRALIA, July 03, 2024 (GLOBE NEWSWIRE) — Immutep Limited<\/a> (ASX: IMM; NASDAQ: IMMP) (\u201cImmutep\u201d or \u201cthe Company\u201d), a clinical-stage biotechnology company developing novel LAG-3 immunotherapies for cancer and autoimmune disease, today announces details for an upcoming oral presentation at the European Society for Medical Oncology (ESMO) Virtual Plenary session on July 11, 2024, featuring new clinical data in patients with negative PD-L1 expression (Cohort B) in the TACTI-003 (KEYNOTE-PNC-34) Phase IIb trial, and a webcast to discuss these clinical results.<\/p>\n

ESMO Virtual Plenaries are monthly presentations of the latest, original scientific data, including \u201cPhase II trials which<\/em> demonstrate remarkable therapeutic benefit, scientific insight or progress in an area of unmet need\u201d.<\/em> The oral presentation will announce the substantially improved overall response rate, as advised 27 June 2024, and additional data in patients with first line head and neck squamous cell carcinoma who have negative PD-L1 (Cohort B).<\/p>\n

Details for <\/strong>the ESMO Plenary presentation<\/strong>
Title:<\/strong>\u00a0 \u00a0 \u00a0 \u00a0Eftilagimod Alpha (Soluble LAG-3) & Pembrolizumab in First-Line Recurrent or Metastatic Head & Neck Squamous Cell Carcinoma: Primary Results from Cohort B (CPS <1) of the TACTI-003 Study
Presenter:<\/strong>\u00a0 \u00a0Dr. Robert Metcalf, The Christie NHS Foundation Trust, Manchester, U.K.
Format:<\/strong>\u00a0 \u00a0 \u00a0 \u00a0Oral Presentation
Date\/Time:<\/strong>\u00a018:30-19:30 Central European Time (CEST), July 11, 2024<\/p>\n

Webcast Details<\/strong>
Immutep will host a webcast to discuss the clinical data. A replay of the webcast will be available under the Events section of Immutep\u2019s website after the event.<\/p>\n

Date\/Time:<\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Friday, July 12, at 9am AEST (7pm ET July 11)
Register: <\/strong>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Link to register for webcast<\/a>
Questions: <\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Investors are invited to submit questions in advance via immutep@morrowsodali.com<\/a><\/p>\n

About the TACTI-003 Trial<\/strong>
The TACTI-003 (KEYNOTE-PNC-34) trial is an ongoing Phase IIb study evaluating eftilagimod alfa (efti), Immutep\u2019s proprietary soluble LAG-3 protein and MHC Class II agonist, in combination with MSD\u2019s (Merck & Co., Inc., Rahway, NJ, USA) anti-PD-1 therapy KEYTRUDA\u00ae (pembrolizumab) as first line treatment of recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). The randomized Cohort A portion of the study is evaluating efti in combination with pembrolizumab as compared to pembrolizumab monotherapy in patients with PD-L1 positive (Combined Positive Score [CPS] \u22651) tumours, whereas Cohort B is evaluating efti in combination with pembrolizumab in patients with PD-L1 negative tumours.<\/p>\n

The primary endpoint of the study is Overall Response Rate of evaluable patients according to RECIST 1.1. Secondary endpoints include Overall Survival, Overall Response Rate according to iRECIST, Progression Free Survival, and Duration of Response. For more information about the Phase IIb trial, visit clinicaltrials.gov (NCT04811027).<\/p>\n

About Eftilagimod Alfa (Efti)<\/strong>
Efti is Immutep\u2019s proprietary soluble LAG-3 protein and MHC Class II agonist that stimulates both innate and adaptive immunity for the treatment of cancer. As a first-in-class antigen presenting cell (APC) activator, efti binds to MHC (major histocompatibility complex) Class II molecules on APC leading to activation and proliferation of CD8+ cytotoxic T cells, CD4+ helper T cells, dendritic cells, NK cells, and monocytes. It also upregulates the expression of key biological molecules like IFN-\u01b4 and CXCL10 that further boost the immune system\u2019s ability to fight cancer.<\/p>\n

Efti is under evaluation for a variety of solid tumours including non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), and metastatic breast cancer. Its favourable safety profile enables various combinations, including with anti-PD-[L]1 immunotherapy and\/or chemotherapy. Efti has received Fast Track designation in first line HNSCC and in first line NSCLC from the United States Food and Drug Administration (FDA).<\/p>\n

About Immutep<\/strong>
Immutep is a clinical-stage biotechnology company developing novel LAG-3 immunotherapy for cancer and autoimmune disease. We are pioneers in the understanding and advancement of therapeutics related to Lymphocyte Activation Gene-3 (LAG-3), and our diversified product portfolio harnesses its unique ability to stimulate or suppress the immune response. Immutep is dedicated to leveraging its expertise to bring innovative treatment options to patients in need and to maximise value for shareholders. For more information, please visit www.immutep.com<\/a>.<\/p>\n

KEYTRUDA\u00ae is a registered trademark of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA.<\/p>\n

Australian Investors\/Media:<\/strong>
Catherine Strong, Morrow Sodali
+61 (0)406 759 268; c.strong@morrowsodali.com<\/a><\/p>\n

U.S. Media:<\/strong>
Chris Basta, VP, Investor Relations and Corporate Communications
+1 (631) 318 4000; chris.basta@immutep.com<\/a><\/p>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Company to Host Webcast on 12th July at 9am AEST (7pm ET, 11 July) SYDNEY, AUSTRALIA, July 03, 2024 (GLOBE NEWSWIRE) — Immutep Limited (ASX: IMM; NASDAQ: IMMP) (\u201cImmutep\u201d or \u201cthe Company\u201d), a clinical-stage biotechnology company developing novel LAG-3 immunotherapies for cancer and autoimmune disease, today announces details for an upcoming oral presentation at the […]\n","protected":false},"author":1,"featured_media":56886,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-56885","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"\nImmutep Announces Details for Oral Presentation at ESMO Virtual Plenary Session and Webcast to Discuss Clinical Results - Biz and Live in Saigon<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Immutep Announces Details for Oral Presentation at ESMO Virtual Plenary Session and Webcast to Discuss Clinical Results\" \/>\n<meta property=\"og:description\" content=\"Company to Host Webcast on 12th July at 9am AEST (7pm ET, 11 July) SYDNEY, AUSTRALIA, July 03, 2024 (GLOBE NEWSWIRE) — Immutep Limited (ASX: IMM\" \/>\n<meta property=\"og:url\" content=\"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/\" \/>\n<meta property=\"og:site_name\" content=\"Biz and Live in Saigon\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/SaigonbizGroup\" \/>\n<meta property=\"article:published_time\" content=\"2024-07-03T12:04:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/english.saigonbiz.com\/vn\/wp-content\/uploads\/2024\/07\/Immutep-Limited.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1\" \/>\n\t<meta property=\"og:image:height\" content=\"1\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/#\/schema\/person\/267b348e6cf32a66aab33637c2d399a6\"},\"headline\":\"Immutep Announces Details for Oral Presentation at ESMO Virtual Plenary Session and Webcast to Discuss Clinical Results\",\"datePublished\":\"2024-07-03T12:04:27+00:00\",\"dateModified\":\"2024-07-03T12:04:27+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/\"},\"wordCount\":727,\"publisher\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/#organization\"},\"articleSection\":[\"Pr Newswire\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/\",\"url\":\"https:\/\/english.saigonbiz.com\/vn\/immutep-announces-details-for-oral-presentation-at-esmo-virtual-plenary-session-and-webcast-to-discuss-clinical-results\/\",\"name\":\"Immutep Announces Details for Oral Presentation at ESMO Virtual Plenary Session and Webcast to Discuss Clinical Results - 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