{"id":71598,"date":"2025-09-01T00:03:42","date_gmt":"2025-09-01T00:03:42","guid":{"rendered":"https:\/\/english.saigonbiz.com.vn\/2025\/09\/01\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/"},"modified":"2025-09-01T00:03:42","modified_gmt":"2025-09-01T00:03:42","slug":"cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025","status":"publish","type":"post","link":"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/","title":{"rendered":"Cytokinetics Presents New Data Related to Aficamten at the European Society of Cardiology Congress 2025"},"content":{"rendered":"
\n

Additional Data from MAPLE-HCM Shows Aficamten\u00a0<\/em>Improves Cardiac Structure and Function Compared to Metoprolol;\u00a0<\/em>Simultaneous Publication in the Journal of the American College of Cardiology<\/em><\/p>\n

New Analysis Shows Annual Incidence Rate of Atrial Fibrillation with Aficamten is 1.5%,\u00a0<\/em>Consistent with Expected Rates in Prediction Model of Patients with HCM;\u00a0<\/em>Simultaneous Publication in Heart Rhythm<\/em><\/p>\n

Longer-Term Data Presented Consistent with Previously Reported Safety Profile of Aficamten <\/em><\/p>\n

Company to Host Investor Event and Webcast Tuesday September 2, 2025, at\u00a08:30 AM Eastern Time<\/em><\/p>\n

SOUTH SAN FRANCISCO, Calif., Aug. 31, 2025 (GLOBE NEWSWIRE) — Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that additional data related to aficamten\u00a0<\/em>were presented at the European Society of Cardiology Congress 2025 in Madrid, Spain, including a pre-specified analysis of the effect of aficamten <\/em>on cardiac structure and function from MAPLE-HCM (M<\/em><\/strong>etoprolol<\/em> vs A<\/em><\/strong>ficamten<\/em> in P<\/strong>atients with L<\/strong>VOT Obstruction on\u00a0E<\/strong>xercise Capacity in HCM<\/strong>), which was simultaneously published in the Journal of the American College of Cardiology<\/em>1<\/sup>, as well as a Late Breaking Clinical Science presentation related to the incidence and impact of atrial fibrillation (AF) associated with aficamten, <\/em>which was simultaneously published in Heart Rhythm<\/em>.2<\/sup><\/p>\n

\u201cThe echocardiographic results from MAPLE-HCM elaborate on the superiority of aficamten <\/em>compared to the current standard-of-care metoprolol <\/em>as was previously reported in the primary efficacy analyses,\u201d said Fady I. Malik, M.D., Ph.D., Cytokinetics\u2019 Executive Vice President of Research & Development. \u201cThe additional data presented at the ESC Congress 2025 continue to strengthen the evidence base supporting the overall safety profile of aficamten, <\/em>including as has been observed with a real-world dosing strategy.\u201d<\/p>\n

Aficamten<\/em> is an investigational drug candidate currently under regulatory review in the U.S.; the Food and Drug Administration (FDA) is reviewing a New Drug Application (NDA) for aficamten<\/em> with a Prescription Drug User Fee Act (PDUFA) target action date of December 26, 2025.<\/p>\n

Additional Analysis from MAPLE-HCM Assesses Effect of <\/strong>Aficamten<\/em><\/strong> Compared to <\/strong>Metoprolol<\/em><\/strong> on Cardiac Structure and Function <\/strong><\/p>\n

Dr. Sheila Hegde, M.D., M.P.H., Assistant Professor, UT Southwestern Medical Center, Dallas, TX, Affiliate Faculty, Brigham and Women’s Hospital, Boston, MA, presented a pre-specified echocardiographic analysis assessing the effect of treatment with aficamten <\/em>relative to metoprolol<\/em> on cardiac structure and function from MAPLE-HCM.<\/p>\n

In addition to primary results of MAPLE-HCM presented by Dr. Garcia Pavia at the European Society of Cardiology Congress 2025, aficamten<\/em> was also shown to be superior to metoprolol<\/em> at improving measures of diastolic function and reducing the likelihood of mitral valve systolic anterior motion (SAM) and mitral valve leaflet-septal contact, the primary contributor to left ventricular outflow tract (LVOT) obstruction (Figure 1) (all p<0.001). There was a significant decrease in maximal wall thickness in patients treated with aficamten<\/em> compared to those treated with metoprolol<\/em> (treatment corrected difference = -1.01 mm [95% CI -1.8 to -0.2, p=0.015]) although the reduction in left ventricular mass index (LVMI) was not significantly different comparing aficamten<\/em> to metoprolol<\/em>. One (1.1%) patient treated with aficamten<\/em> experienced transient left ventricular ejection fraction (LVEF) <50% without heart failure or treatment interruption. These data were simultaneously published in the Journal of the American College of Cardiology.<\/em>1<\/em><\/sup><\/p>\n

\"MAPLE-HCM<\/p>\n

Long-Term Treatment with <\/strong>Aficamten<\/em><\/strong> Does Not Appear to Increase Risk of Atrial Fibrillation in Patients with Obstructive Hypertrophic Cardiomyopathy<\/strong><\/p>\n

Ahmad Masri, M.D., MS, Director of the Hypertrophic Cardiomyopathy Center at Oregon Health & Science University, presented a new analysis of the incidence and impact of AF in patients with obstructive hypertrophic cardiomyopathy (oHCM) in a Late Breaking Clinical Science Session outlining the experience of patients treated with aficamten<\/em> in the open-label study, FOREST-HCM (F<\/strong>ollow-up, O<\/strong>pen-Label, R<\/strong>esearch E<\/strong>valuation of S<\/strong>ustained T<\/strong>reatment with Aficamten<\/em> in HCM<\/strong>). These results were also simultaneously published in Heart Rhythm<\/em>.2<\/sup><\/p>\n

Among 173 patients followed for \u226548 weeks, 136 had no history of AF at baseline. Four (2.9%) patients developed new-onset AF during follow-up, with an incidence rate of 1.5% per year. This rate is consistent with expected rates from validated prediction models in patients with HCM, the HCM-AF (3.6% per year) and in healthy individuals, CHARGE-AF (1.4% per year). Importantly, the clinical impact of new AF was minimal, with one patient experiencing LVEF <50% at the time of the arrhythmia event, and none experiencing heart failure. In three of these patients, sinus rhythm was restored without the need for antiarrhythmic medications or an atrial fibrillation ablation procedure. One asymptomatic patient did not undergo an attempt to restore normal sinus rhythm. Of the 37 patients with history of AF at baseline, 10 experienced recurrent AF episodes (27.0%), none of which were associated with LVEF <50% or heart failure. In patients experiencing AF, the improvement in symptoms and hemodynamics, and the safety profile of aficamten<\/em> was no different than the overall cohort studied. Consequently, the authors concluded that long-term treatment with aficamten<\/em> did not appear to increase the risk for AF, nor did the presence of AF negatively impact clinical outcomes.<\/p>\n

New Data from FOREST-HCM on the Longer-Term Safety and Efficacy of Treatment with <\/strong>Aficamten<\/em><\/strong> Consistent with Previous Reports<\/strong><\/p>\n

Sara Saberi, M.D., M.S., Associate Professor of Internal Medicine, University of Michigan Health Frankel Cardiovascular Center, presented new data related to the safety and long-term use of aficamten <\/em>in FOREST-HCM.<\/p>\n

FOREST-HCM, the open-label extension clinical study, enrolled 296 patients with oHCM from May 28, 2021, through the data cutoff of August 31, 2024. The total cumulative exposure to aficamten<\/em> was 352 patient-years over a mean follow-up of 62 weeks and maximum follow-up of 170 weeks. Consistent with previously presented data from FOREST-HCM, this updated data set demonstrates that long-term treatment with aficamten<\/em> is associated with early and sustained hemodynamic and clinical benefits, along with a low incidence of new-onset AF and LVEF <50%.<\/p>\n

Treatment with aficamten<\/em> resulted in a significant reduction from baseline in site-read Valsalva LVOT-G by Week 12 (resting LVOT-G = -40 mmHg [-42, -39] and Valsalva LVOT-G = -56 mmHg [95% CI -58, -52]; p<0.0001 for both), which was sustained through treatment up to three years with minimal reduction in mean LVEF.<\/p>\n

Long-term treatment with aficamten<\/em> was also associated with reduced symptom burden. At Week 12 (n= 283) and Week 96 (n=44), 69% and 93% of patients, respectively, reported \u22651 New York Heart Association (NYHA) Functional Class improvement from baseline. Patients also experienced a mean increase in the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) of 15 and 16 points (p<0.0001), at each time point respectively. Significant improvements from baseline were also observed in NT-proBNP, a biomarker of cardiac wall stress and high-sensitivity cardiac troponin I (both p<0.0001).<\/p>\n

One patient (0.3%) terminated treatment due to a treatment emergent adverse event of ischemic colitis, determined not to be related to the treatment with aficamten<\/em>. Dose down-titration occurred in 10 (3.4%) patients based on site-read LVEF <50%. None of the site-read instances of LVEF <50% were corroborated by the core lab, and none were associated with a serious event of heart failure. New-onset AF occurred in 3 (1%) patients.<\/p>\n

Updated Integrated Safety Analysis, Including MAPLE-HCM, Provides Additional Evidence on the Safety and Tolerability of <\/strong>Aficamten <\/em><\/strong>in oHCM<\/strong><\/p>\n

A new integrated safety analysis from three clinical trials of aficamten<\/em> presented by Dr. Masri provided additional safety and tolerability evidence. The analysis included data from the Phase 2 clinical trial, REDWOOD-HCM, two Phase 3 clinical trials, SEQUOIA-HCM and MAPLE-HCM, and the open-label extension clinical study, FOREST-HCM.<\/p>\n

In this integrated safety analysis of 463 participants with oHCM and almost 700 patient-years of exposure, aficamten<\/em> was shown to be well-tolerated and had an adverse event profile similar to placebo. There remains a low incidence of LVEF <50% over extended exposure, with no occurrences associated with a serious event of heart failure. A low incidence of new-onset atrial fibrillation (1.9%) was observed with aficamten<\/em>, at a rate comparable to placebo (2%) and metoprolol<\/em> (3.4%). There were no permanent discontinuations related to treatment with aficamten. <\/em><\/p>\n

Investor Webcast Information<\/strong><\/p>\n

Cytokinetics will host an investor webcast on September 2, 2025, at 8:30 AM Eastern Time to discuss the primary results from MAPLE-HCM and other data presented at the European Society of Cardiology Congress 2025. Interested parties can register online at\u00a0https:\/\/cytokinetics-esc-2025.open-exchange.net\/<\/a>. The live webcast will be available on the Investors & Media section of the\u00a0Cytokinetics\u00a0website at\u00a0www.cytokinetics.com<\/a>. A replay of the webcast will be archived on the\u00a0Cytokinetics\u00a0website for six months.<\/p>\n

About <\/strong>Aficamten <\/em><\/strong><\/p>\n

Aficamten<\/em> is an investigational selective, small molecule cardiac myosin inhibitor discovered following an extensive chemical optimization program that was conducted with careful attention to therapeutic index and pharmacokinetic properties.3<\/sup> Aficamten<\/em> was designed to reduce the number of active actin-myosin cross bridges during each cardiac cycle and consequently suppress the myocardial hypercontractility that is associated with HCM. In preclinical models, aficamten<\/em> reduced myocardial contractility by binding directly to cardiac myosin at a distinct and selective allosteric binding site, thereby preventing myosin from entering a force producing state.<\/p>\n

The development program for aficamten<\/em> is assessing its potential as a treatment that improves exercise capacity as measured by peak oxygen uptake (pVO2<\/sub>) and relieves symptoms in patients with HCM. Aficamten<\/em> was evaluated in SEQUOIA-HCM, a positive pivotal Phase 3 clinical trial in patients symptomatic obstructive hypertrophic cardiomyopathy (HCM). Aficamten<\/em> received Breakthrough Therapy Designation for the treatment of symptomatic HCM from the U.S. Food & Drug Administration (FDA) and for the treatment of symptomatic obstructive HCM from the National Medical Products Administration (NMPA) in China.<\/p>\n

Aficamten<\/em> is also currently being evaluated in ACACIA-HCM, a Phase 3 clinical trial of aficamten<\/em> in patients with non-obstructive HCM; CEDAR-HCM, a clinical trial of aficamten <\/em>in a pediatric population with oHCM; and FOREST-HCM, an open-label extension clinical study of aficamten <\/em>in patients with HCM.<\/p>\n

This communication contains a summary of new data related to the clinical development of aficamten<\/em> presented at the European Society of Cardiology 2025 Congress. Aficamten<\/em> is an investigational drug and is not approved by any regulatory agency. Its safety and efficacy have not been established. Aficamten<\/em> is currently under regulatory review in the U.S., where the FDA is reviewing a New Drug Application (NDA) for aficamten<\/em> with a Prescription Drug User Fee Act (PDUFA) target action date of December 26, 2025. Additionally, the European Medicines Agency (EMA) is reviewing a Marketing Authorization Application (MAA) for aficamten<\/em>, and The Center for Drug Evaluation (CDE) of the\u202fChina National Medical Products Administration (NMPA) is reviewing an NDA for aficamten<\/em> with Priority Review.<\/p>\n

About Hypertrophic Cardiomyopathy<\/strong><\/p>\n

Hypertrophic cardiomyopathy (HCM) is a disease in which the heart muscle (myocardium) becomes abnormally thick (hypertrophied). The thickening of cardiac muscle leads to the inside of the left ventricle becoming smaller and stiffer, and thus the ventricle becomes less able to relax and fill with blood. This ultimately limits the heart\u2019s pumping function, resulting in reduced exercise capacity and symptoms including chest pain, dizziness, shortness of breath, or fainting during physical activity. HCM is the most common monogenic inherited cardiovascular disorder, with approximately 280,000 patients diagnosed, however, there are an estimated 400,000-800,000 additional patients who remain undiagnosed in the\u00a0U.S.4<\/sup>,<\/sup>5<\/sup>,<\/sup>6<\/sup>\u00a0Two-thirds of patients with HCM have obstructive HCM (oHCM), where the thickening of the cardiac muscle leads to left ventricular outflow tract (LVOT) obstruction, while one-third have non-obstructive HCM (nHCM), where blood flow isn\u2019t impacted, but the heart muscle is still thickened. People with HCM are at high risk of also developing cardiovascular complications including atrial fibrillation, stroke and mitral valve disease.7<\/sup>\u00a0People with HCM are at risk for potentially fatal ventricular arrhythmias and it is one of the leading causes of sudden cardiac death in younger people or athletes.8<\/sup>\u00a0A subset of patients with HCM are at high risk of progressive disease leading to dilated cardiomyopathy and heart failure necessitating cardiac transplantation.<\/p>\n

About Cytokinetics<\/strong><\/p>\n

Cytokinetics\u00a0is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.\u00a0Cytokinetics\u00a0is readying for potential regulatory approvals and commercialization of\u00a0aficamten<\/em>,\u00a0a cardiac myosin inhibitor, following positive results from SEQUOIA-HCM, the pivotal Phase 3 clinical trial in patients with obstructive hypertrophic cardiomyopathy (HCM).\u00a0Aficamten<\/em>\u00a0is also being evaluated in additional clinical trials enrolling patients with obstructive and non-obstructive HCM.\u00a0In addition,\u00a0Cytokinetics\u00a0is developing\u00a0omecamtiv mecarbil<\/em>, a cardiac myosin activator, in patients with heart failure with severely reduced ejection fraction (HFrEF), ulacamten<\/em>, a cardiac myosin inhibitor with a mechanism of action distinct from\u00a0aficamten<\/em>,\u00a0for the potential treatment of heart failure with preserved ejection fraction (HFpEF) and CK-089, a fast skeletal muscle troponin activator with potential therapeutic application to a specific type of muscular dystrophy and other conditions of impaired skeletal muscle function.<\/p>\n

For additional information about Cytokinetics, visit www.cytokinetics.com<\/a>\u00a0and follow us on X<\/a>, LinkedIn<\/a>, Facebook<\/a> and YouTube<\/a>.<\/p>\n

Forward-Looking Statements<\/strong><\/p>\n

This press release contains forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the “Act”). Cytokinetics disclaims any intent or obligation to update these forward-looking statements and claims the protection of the Act’s Safe Harbor for forward-looking statements. Examples of such statements include, but are not limited to, statements relating to any of our clinical trials, statements relating to the potential benefits of\u00a0aficamten<\/em>\u00a0or any of our other drug candidates, or our ability to obtain regulatory approval for aficamten<\/em> in any jurisdiction by any particular date, if ever. Cytokinetics’ research and development activities; the design, timing, results, significance and utility of preclinical and clinical results; and the properties and potential benefits of Cytokinetics’ other drug candidates. Such statements are based on management’s current expectations, but actual results may differ materially due to various risks and uncertainties, including, but not limited to, potential difficulties or delays in the development, testing, regulatory approvals for trial commencement, progression or product sale or manufacturing, or production of Cytokinetics’ drug candidates that could slow or prevent clinical development or product approval; Cytokinetics’ drug candidates may have adverse side effects or inadequate therapeutic efficacy; the FDA or foreign regulatory agencies may delay or limit Cytokinetics’ ability to conduct clinical trials; Cytokinetics may be unable to obtain or maintain patent or trade secret protection for its intellectual property; standards of care may change, rendering Cytokinetics’ drug candidates obsolete; and competitive products or alternative therapies may be developed by others for the treatment of indications Cytokinetics’ drug candidates and potential drug candidates may target. For further information regarding these and other risks related to Cytokinetics’ business, investors should consult Cytokinetics’ filings with the Securities and Exchange Commission.<\/p>\n

CYTOKINETICS\u00ae and the CYTOKINETICS and C-shaped logo are registered trademarks of Cytokinetics in the U.S. and certain other countries.<\/p>\n

Contact:
Cytokinetics
Diane Weiser
Senior Vice President, Corporate Affairs
(415) 290-7757<\/p>\n

References:<\/p>\n

    \n
  1. Hegde, SM. Effect of Aficamten<\/em> Compared with Metoprolol on Echocardiographic Measures in Symptomatic Obstructive Hypertrophic Cardiomyopathy: MAPLE-HCM. JACC. 2025. DOI: https:\/\/www.jacc.org\/doi\/10.1016\/j.jacc.2025.08.022<\/a>.<\/li>\n
  2. Rowin, EJ, et al. Low Incidence of Atrial Fibrillation in Patients with Obstructive HCM Treated with Aficamten<\/em>: An Analysis from the REDWOOD-HCM, SEQUOIA-HCM and FOREST-HCM Trials. Heart Rhythm. 2025.<\/li>\n
  3. Chuang C, Collibee S, Ashcraft L, et al. Discovery of Aficamten<\/em> (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. J Med Chem. 2021;64(19):14142\u201314152. https:\/\/doi.org\/10.1021\/acs.jmedchem.1c01290<\/li>\n
  4. CVrg: Heart Failure 2020-2029, p 44; Maron et al. 2013 DOI: 10.1016\/S0140-6736(12)60397-3; Maron et al 2018 10.1056\/NEJMra1710575<\/li>\n
  5. Symphony Health 2016-2021 Patient Claims Data DoF;<\/li>\n
  6. Maron MS, Hellawell JL, Lucove JC, Farzaneh-Far R, Olivotto I. Occurrence of Clinically Diagnosed Hypertrophic Cardiomyopathy in the United States. Am J Cardiol. 2016; 15;117(10):1651-1654.<\/li>\n
  7. Gersh, B.J., Maron, B.J., Bonow, R.O., Dearani, J.A., Fifer, M.A., Link, M.S., et al. 2011 ACCF\/AHA guidelines for the diagnosis and treatment of hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation\/American Heart Association Task Force on practice guidelines. Journal of the American College of Cardiology and Circulation, 58, e212-260.<\/li>\n
  8. Hong Y, Su WW, Li X. Risk factors of sudden cardiac death in hypertrophic cardiomyopathy. Current Opinion in Cardiology. 2022 Jan 1;37(1):15-21<\/li>\n<\/ol>\n

    A photo accompanying this announcement is available at https:\/\/www.globenewswire.com\/NewsRoom\/AttachmentNg\/295e0d2b-533f-4f00-be6f-2b035a16d416<\/a><\/p>\n

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    Additional Data from MAPLE-HCM Shows Aficamten\u00a0Improves Cardiac Structure and Function Compared to Metoprolol;\u00a0Simultaneous Publication in the Journal of the American College of Cardiology New Analysis Shows Annual Incidence Rate of Atrial Fibrillation with Aficamten is 1.5%,\u00a0Consistent with Expected Rates in Prediction Model of Patients with HCM;\u00a0Simultaneous Publication in Heart Rhythm Longer-Term Data Presented Consistent with […]\n","protected":false},"author":1,"featured_media":71599,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-71598","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"\nCytokinetics Presents New Data Related to Aficamten at the European Society of Cardiology Congress 2025 - Biz and Live in Saigon<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cytokinetics Presents New Data Related to Aficamten at the European Society of Cardiology Congress 2025\" \/>\n<meta property=\"og:description\" content=\"Additional Data from MAPLE-HCM Shows Aficamten\u00a0Improves Cardiac Structure and Function Compared to Metoprolol;\u00a0Simultaneous Publication in the Journ\" \/>\n<meta property=\"og:url\" content=\"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/\" \/>\n<meta property=\"og:site_name\" content=\"Biz and Live in Saigon\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/SaigonbizGroup\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-01T00:03:42+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/english.saigonbiz.com\/vn\/wp-content\/uploads\/2025\/09\/maple-hcm-echo-figure-1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"607\" \/>\n\t<meta property=\"og:image:height\" content=\"452\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"13 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/#\/schema\/person\/267b348e6cf32a66aab33637c2d399a6\"},\"headline\":\"Cytokinetics Presents New Data Related to Aficamten at the European Society of Cardiology Congress 2025\",\"datePublished\":\"2025-09-01T00:03:42+00:00\",\"dateModified\":\"2025-09-01T00:03:42+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/\"},\"wordCount\":2625,\"publisher\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/#organization\"},\"articleSection\":[\"Pr Newswire\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/\",\"url\":\"https:\/\/english.saigonbiz.com\/vn\/cytokinetics-presents-new-data-related-to-aficamten-at-the-european-society-of-cardiology-congress-2025\/\",\"name\":\"Cytokinetics Presents New Data Related to Aficamten at the European Society of Cardiology Congress 2025 - 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