{"id":79317,"date":"2026-04-09T12:01:05","date_gmt":"2026-04-09T12:01:05","guid":{"rendered":"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/"},"modified":"2026-04-09T12:01:05","modified_gmt":"2026-04-09T12:01:05","slug":"kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026","status":"publish","type":"post","link":"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/","title":{"rendered":"Kura Oncology to Present Darlifarnib Plus Cabozantinib Data in Patients with Clear Cell Renal Cell Carcinoma Previously Treated with Cabozantinib at IKCS Europe 2026"},"content":{"rendered":"<div>\n<p align=\"center\"><em>Data build on findings presented at ESMO 2025 and support potential of darlifarnib to overcome resistance and resensitize tumors to VEGFR TKI therapy<\/em><\/p>\n<p align=\"center\"><em>Virtual investor call on April 17, 2026, at 7:30 a.m. PT<\/em><em>\u00a0\/\u00a0<\/em><em>10:30 a.m. ET \/ 4:30 p.m. CEST<\/em><\/p>\n<p>SAN DIEGO, April  09, 2026  (GLOBE NEWSWIRE) &#8212; Kura Oncology, Inc. (Nasdaq: KURA), a biopharmaceutical company focused on precision medicines for the treatment of cancer, today announced it will present updated data from its ongoing FIT-001 clinical trial (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=G6GVc92r8t0ujYQGZ6RvZRj7DWnb-jStlg-KlzlHYMq7O8C0Lr4cW-Rsg_FLqbMj3tEHZsyIeUqTsSLdbnxa-5QKU7yMUP0dt5CanPQxCTMOTiQeZMumMtJ9bedGRvJF\" rel=\"nofollow\" target=\"_blank\" title=\"NCT 06026410)\">NCT 06026410)<\/a> evaluating darlifarnib (KO-2806) in combination with cabozantinib in patients with advanced clear cell renal cell carcinoma at the International Kidney Cancer Symposium (IKCS) Europe 2026 in Paris, France.<\/p>\n<p>The data to be presented build on earlier findings from the FIT-001 study reported at the 2025 European Society for Medical Oncology (ESMO) Congress, where the combination of darlifarnib and cabozantinib demonstrated encouraging clinical activity and a manageable safety profile in patients with advanced renal cell carcinoma.<\/p>\n<p><strong>IKCS Europe 2026 Presentation Details<\/strong><\/p>\n<p>Title: <em>Farnesyl transferase inhibitor (FTI) darlifarnib (KO-2806) combined with cabozantinib (cabo) in clear cell renal cell carcinoma (ccRCC) patients after prior exposure to cabo: Preliminary Phase 1 results from FIT-001<\/em><\/p>\n<p>Abstract Session: 7<br \/>Date: April 17, 2026<br \/>Time: 3:30 p.m. \u2013 4:30 p.m. CEST<\/p>\n<p align=\"left\"><strong>Virtual Investor Event<br \/><\/strong>Kura will host a webcast and conference call on April 17, 2026, at 7:30 am PT \/ 10:30 am ET \/ 4:30 pm CEST featuring management and a clinical investigator from the darlifarnib program. The live webcast and replay will be available on the Company\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=PI-vPMizx4LT8ssc9AiG-co9jW8-1exO39S2WFjdA37ju6yuDF8zHXn5_kHhZdzQ6EwCsjINlNZeaKInQaxH2GRrlQMTIlnWYfv6CgOO0SA=\" rel=\"nofollow\" target=\"_blank\" title=\"www.kuraoncology.com\">www.kuraoncology.com<\/a> under the Investors tab in the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=dC1lkGMfQM9rfeNA7XHVy8GThpP_gk_HK5aunZGHGzPMOKujXkyREfqqPXafhqWQMctsoEvqzzDbTA-BZLJUOMbG32ZW5NRmd6kr0NVszcDL5yQoZOoBrfMj26766zsHgDmVeLNJw0Paw478mFJZGw==\" rel=\"nofollow\" target=\"_blank\" title=\"Events and Presentations\">Events and Presentations<\/a> section. \u00a0<\/p>\n<p><strong>About darlifarnib<\/strong><br \/>Darlifarnib is a next-generation farnesyl transferase inhibitor (FTI) designed to inhibit farnesylation of RHEB and suppress mTORC1 signaling. This mechanism has potential to enhance the activity of multiple targeted therapies, including VEGFR-targeted therapies such as cabozantinib.<\/p>\n<p><strong>About\u00a0Kura Oncology<\/strong><br \/>Kura Oncology\u00a0is a biopharmaceutical company committed to realizing the promise of precision medicines for the treatment of cancer. Kura\u2019s pipeline of small molecule drug candidates is designed to target cancer signaling pathways and address high-need hematologic malignancies and solid tumors. Kura developed and is commercializing KOMZIFTI&#x2122; (ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory\u00a0<em>NPM1<\/em>-mutated acute myeloid leukemia, and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. For additional information, please visit the Kura website at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=md5UQrOnWKA5S0qT20S_cvbmhEwvG8n8d7ytWwiKFWEwUzRN72XwamAL4mTUtznpTMzHaMvXZDkvY6jfvXPq-iTZb-_Z6IWO_OX70Zl_5vQ=\" rel=\"nofollow\" target=\"_blank\" title=\"\">https:\/\/kuraoncology.com\/<\/a>\u00a0and follow us on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=bEyrrkMMhOiWx2ag28v2MoKKJQcEvPinvUZ9VxVHkQtOcSWFYdstsiKESJLapwBYl0BBxPU2tzMLjGMqB_uJiw==\" rel=\"nofollow\" target=\"_blank\" title=\"X\">X<\/a>\u00a0and\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=pfTew-DC7skyqWbjxwBwgE8qdVqVZzCfBld6nJj3KzV_cDW3SVbcn2LJp_OwwfCL75Ngmv5TcOfhz2ZEvktxI6Y7Z9M94hVPQTE7yo4PY_VkVGFQCb-1uB8CLe7Mrl4I\" rel=\"nofollow\" target=\"_blank\" title=\"LinkedIn\">LinkedIn<\/a>.<\/p>\n<p><strong>Forward-Looking Statements\u00a0<\/strong><br \/>This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include, among other things, statements regarding Kura\u2019s presentation of FIT-001 data at IKCS Europe 2026, the therapeutic potential of the combination of darlifarnib and cabozantinib in patients with clear cell renal cell carcinoma, and the potential of darlifarnib to overcome resistance and resensitize tumors to VEGFR TKI therapy and to enhance the activity of multiple targeted therapies. Factors that may cause actual results to differ materially include the risk that compounds that appeared promising in early research or clinical trials do not demonstrate safety and\/or efficacy in later preclinical studies or clinical trials, the risk that Kura may not obtain approval to market its product candidates, uncertainties associated with performing clinical trials, regulatory filings, and other interactions with regulatory bodies, and other risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. You are urged to consider statements that include the words \u201cmay,\u201d \u201cwill,\u201d \u201cwould,\u201d \u201ccould,\u201d \u201cshould,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d \u201cprojects,\u201d \u201cpromise,\u201d \u201cpotential,\u201d \u201cexpects,\u201d \u201cplans,\u201d \u201canticipates,\u201d \u201cintends,\u201d \u201ccontinues,\u201d \u201cdesigned,\u201d \u201cgoal,\u201d or the negative of those words or other comparable words to be uncertain and forward-looking. For a further list and description of the risks and uncertainties Kura faces, please refer to Kura\u2019s periodic and other filings with the Securities and Exchange Commission, which are available at www.sec.gov. Such forward-looking statements are current only as of the date they are made, and Kura assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.\u00a0<\/p>\n<p><strong>Kura Contact<\/strong><br \/>Investors and Media:<br \/>Greg Mann<br \/>858-987-4046<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=KkNizfp2tUfxratVY3Ywb4mSBE8QGZmyULv6Nin06beg2rVBjEKSw7oQp52v2DpvwYE8ZzMqdy46qyzavgvNEtrmjVRM_RUwO8yulKyNyuI=\" rel=\"nofollow\" target=\"_blank\" title=\"gmann@kuraoncology.com\">gmann@kuraoncology.com<\/a><\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/Y2U5M2RjYzMtMzY1NS00Yjg2LTg1ZWItZjIxZjViNmE4NDI2LTEwMjg3NjgtMjAyNi0wNC0wOS1lbg==\/tiny\/Kura-Oncology-Inc-.png\" referrerpolicy=\"no-referrer-when-downgrade\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Data build on findings presented at ESMO 2025 and support potential of darlifarnib to overcome resistance and resensitize tumors to VEGFR TKI therapy Virtual investor call on April 17, 2026, at 7:30 a.m. PT\u00a0\/\u00a010:30 a.m. ET \/ 4:30 p.m. CEST SAN DIEGO, April 09, 2026 (GLOBE NEWSWIRE) &#8212; Kura Oncology, Inc. (Nasdaq: KURA), a biopharmaceutical [&#8230;]\n","protected":false},"author":1,"featured_media":79226,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-79317","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.6 (Yoast SEO v21.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Kura Oncology to Present Darlifarnib Plus Cabozantinib Data in Patients with Clear Cell Renal Cell Carcinoma Previously Treated with Cabozantinib at IKCS Europe 2026 - Biz and Live in Saigon<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kura Oncology to Present Darlifarnib Plus Cabozantinib Data in Patients with Clear Cell Renal Cell Carcinoma Previously Treated with Cabozantinib at IKCS Europe 2026\" \/>\n<meta property=\"og:description\" content=\"Data build on findings presented at ESMO 2025 and support potential of darlifarnib to overcome resistance and resensitize tumors to VEGFR TKI therapy\" \/>\n<meta property=\"og:url\" content=\"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/\" \/>\n<meta property=\"og:site_name\" content=\"Biz and Live in Saigon\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/SaigonbizGroup\" \/>\n<meta property=\"article:published_time\" content=\"2026-04-09T12:01:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/english.saigonbiz.com\/vn\/wp-content\/uploads\/2026\/04\/sgb-media-kit-2026.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1075\" \/>\n\t<meta property=\"og:image:height\" content=\"716\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/#\/schema\/person\/267b348e6cf32a66aab33637c2d399a6\"},\"headline\":\"Kura Oncology to Present Darlifarnib Plus Cabozantinib Data in Patients with Clear Cell Renal Cell Carcinoma Previously Treated with Cabozantinib at IKCS Europe 2026\",\"datePublished\":\"2026-04-09T12:01:05+00:00\",\"dateModified\":\"2026-04-09T12:01:05+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/\"},\"wordCount\":731,\"publisher\":{\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/#organization\"},\"articleSection\":[\"Pr Newswire\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/\",\"url\":\"https:\/\/english.saigonbiz.com\/vn\/kura-oncology-to-present-darlifarnib-plus-cabozantinib-data-in-patients-with-clear-cell-renal-cell-carcinoma-previously-treated-with-cabozantinib-at-ikcs-europe-2026\/\",\"name\":\"Kura Oncology to Present Darlifarnib Plus Cabozantinib Data in Patients with Clear Cell Renal Cell Carcinoma Previously Treated with Cabozantinib at IKCS Europe 2026 - 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